Article

Reduced cue-induced reinstatement of cocaine-seeking behavior in Plcb1+/- mice

2020-06-19

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background and Purpose</h4> Cocaine addiction causes serious health problems and no effective treatment is available yet. We previously identified a genetic risk variant for cocaine addiction in the PLCB1 gene and found this gene upregulated in postmortem brains of cocaine abusers and in human dopaminergic neuron-like cells after an acute cocaine exposure. Here, we functionally tested the...

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Literature Corpus work: 67f9ccd1-d957-5712-ae56-7cc86f907ed6
DOI: 10.1101/2020.06.18.158964

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