Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of the PLCB1 gene with drug dependence.

Scientific reports - 31 Aug 2017

Cabana-Domínguez Judit, Roncero Carlos, Pineda-Cirera Laura, Palma-Álvarez R Felipe, Ros-Cucurull Elena, Grau-López Lara, Esojo Abderaman, Casas Miquel, Arenas Concepció, Ramos-Quiroga Josep Antoni, Ribasés Marta, Fernàndez-Castillo Noèlia, Cormand Bru

Abstract excerpt

Genetic factors involved in the susceptibility to drug addiction still remain largely unknown. MiRNAs seem to play key roles in the drug-induced plasticity of the brain that likely drives the emergence of addiction. In this work we explored the role of miRNAs in drug addiction. With this aim, we selected 62 SNPs located in the 3'UTR of target genes that are predicted to alter the binding of miRNA molecules and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Cell Line, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cocaine-Related Disorders

Share to MicroRNAs

Share to Neurons

Share to Nucleus Accumbens

Share to Phospholipase C beta

Share to Up-Regulation

Source

Open in PubMed Open full text

Identifiers

PMID: 28860459
DOI: 10.1038/s41598-017-10207-2
PMCID: PMC5579249

Genes

PLCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of the PLCB1 gene with drug dependence.PMID 28860459Read ↗

Evaluation of previous substance dependence genome-wide significant findings in a Spanish sample.Semantic proximity Read ↗

Reduced cue-induced reinstatement of cocaine-seeking behavior in Plcb1+/- miceSemantic proximity Read ↗

Reduced cue-induced reinstatement of cocaine-seeking behavior in Plcb1+/- miceSemantic proximity Read ↗

Molecular genetics of cocaine use disorders in humansSemantic proximity Read ↗

Exploring allele specific methylation in drug dependence susceptibility.Semantic proximity Read ↗

MiR-9, miR-153 and miR-124 are down-regulated by acute exposure to cocaine in a dopaminergic cell model and may contribute to cocaine dependence.Semantic proximity Read ↗

Genetic Architecture and Molecular Neuropathology of Human Cocaine Addiction.Semantic proximity Read ↗

Genetic variants in the cocaine- and amphetamine-regulated transcript gene (CARTPT) and cocaine dependence.Semantic proximity Read ↗

The Piccolo Intronic Single Nucleotide Polymorphism rs13438494 Regulates Dopamine and Serotonin Uptake and Shows Associations with Dependence-Like Behavior in Genomic Association Study.Semantic proximity Read ↗

Single- and multilocus allelic variants within the GABA(B) receptor subunit 2 (GABAB2) gene are significantly associated with nicotine dependence.Semantic proximity Read ↗

Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene.Semantic proximity Read ↗

SNP rs1801260 at the 3'UTR miRNA binding region of Clock gene is a risk factor of alcohol addiction: A case-control study in East Indian population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.