Article
Netrin G1: its downregulation in the nucleus accumbens of cocaine-conditioned mice and genetic association in human cocaine dependence.
Addiction biology - 1 Jan 2018
Kelaï Sabah, Ramoz Nicolas, Moalic Jean-Marie, Noble Florence, Mechawar Naguib, Imbeaud Sandrine, Turecki Gustavo, Simonneau Michel, Gorwood Philip, Maussion Gilles
Abstract excerpt
Netrin G1 is a presynaptic ligand involved in axonal projection. Although molecular mechanisms underlying cocaine addiction are still poorly understood, Netrin G1 might have a role as a regulator of anxiety, fear and spatial memory, behavioural traits impaired in the context of cocaine exposure. In this study, the Netrin G1 (Ntng1) expression was investigated in the nucleus accumbens of mice primarily conditioned...
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