Article

Antibiotic-induced accumulation of lipid II sensitizes bacteria to antimicrobial fatty acids

2022-05-03

Abstract excerpt

Antibiotic tolerance and antibiotic resistance are the two major obstacles to the efficient and reliable treatment of bacterial infections. Identifying antibiotic adjuvants that sensitize resistant and tolerant bacteria to antibiotic killing may lead to the development of superior treatments with improved outcomes. Vancomycin, a lipid II inhibitor, is of major clinical importance for the treatment of Gram-positive...

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Literature Corpus work: 67c5f2ea-6d37-586b-b8b9-09639cba417e
DOI: 10.1101/2022.05.03.490474

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