Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomic and phenotypic adaptations of methicillin resistant Staphylococcus aureus during vancomycin therapy

2 May 2025

Abstract excerpt

Methicillin-resistant Staphylococcus aureus (MRSA) poses a significant global health challenge, particularly associated with serious infections such as bacteremia. Lipoglycopeptide antibiotics, including vancomycin, dalbavancin, and daptomycin, are critical in MRSA treatment. In this study, we analyzed two MRSA isolates (XF1 and XF2) from a bacteremia patient treated with vancomycin. Antimicrobial susceptibility...

Topics

Join the communities discussing this publication.

Antimicrobial Resistance in Staphylococcus
Bacterial biofilms and quorum sensing
Bacterial Identification and Susceptibility Testing

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 40316685
DOI: 10.1038/s41598-025-99639-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomic and phenotypic adaptations of methicillin resistant Staphylococcus aureus during vancomycin therapyPMID 40316685Read ↗

Insights into the molecular basis of reduced vancomycin susceptibility among three prominent Staphylococcus aureus clonal complexesSemantic proximity Read ↗

An induced mutation of ABC-transporter component VraF(K84E) contributes to vancomycin resistance and virulence in Staphylococcus aureus strain MW2.Semantic proximity Read ↗

A novel mutation of walK confers vancomycin-intermediate resistance in methicillin-susceptible Staphylococcus aureus.Semantic proximity Read ↗

Reemergence of antibiotic-resistant Staphylococcus aureus in the genomics eraSemantic proximity Read ↗

Phenotypic and genomic comparisons of highly vancomycin-resistant Staphylococcus aureus strains developed from multiple clinical MRSA strains by in vitro mutagenesis.Semantic proximity Read ↗

A vancomycin resistance-associated WalK(S221P) mutation attenuates the virulence of vancomycin-intermediate Staphylococcus aureus.Semantic proximity Read ↗

Staphylococcus aureus response and adaptation to vancomycin.Semantic proximity Read ↗

Evolution of multidrug resistance during Staphylococcus aureus infection involves mutation of the essential two component regulator WalKR.Semantic proximity Read ↗

The Secondary Resistome of Methicillin-Resistant Staphylococcus aureus to β-Lactam AntibioticsSemantic proximity Read ↗

Mechanisms of vancomycin resistance in Staphylococcus aureus.Semantic proximity Read ↗

“Decoding Mobile Genetic Elements, Virulence Factors, and Antibiotic Resistance Genes Driving Biofilm Formation in MRSA via Network Analysis”Semantic proximity Read ↗

Preliminary analysis of the genetic basis for vancomycin resistance in Staphylococcus aureus strain Mu50.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.