Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prophages divert Staphylococcus aureus defenses against host lipids

4 Nov 2024

Abstract excerpt

Phages are ubiquitous in bacteria, including clinical Staphylococcus aureus, where Sfi 21/Sa3 phages often integrate into the hlb gene, which encodes Hlb sphingomyelinase. This integration acts as a rapid regulatory switch for Hlb production. Our findings suggest that Sfi 21/Sa3 prophages and Hlb activity influence S. aureus fitness by modulating the incorporation of the toxic linoleic acid (C18:2) from serum...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibiotic Resistance in Bacteria
Share to Antimicrobial Resistance in Staphylococcus
Share to RNA and protein synthesis mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39505263
DOI: 10.1016/j.jlr.2024.100693

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prophages divert Staphylococcus aureus defenses against host lipidsPMID 39505263Read ↗

Prophages divert <i>Staphylococcus aureus</i> defenses against host lipidsSemantic proximity Read ↗

Permissive Fatty Acid Incorporation in Host Environments Promotes Staphylococcal Adaptation to FASII AntibioticsSemantic proximity Read ↗

Permissive Fatty Acid Incorporation Promotes Staphylococcal Adaptation to FASII Antibiotics in Host EnvironmentsSemantic proximity Read ↗

Staphylococcus aureus Utilizes Host-Derived Lipoprotein Particles as Sources of Fatty Acids.Semantic proximity Read ↗

Lipase-mediated detoxification of host-derived antimicrobial fatty acids by Staphylococcus aureusSemantic proximity Read ↗

Lipase-mediated detoxification of host-derived antimicrobial fatty acids by <i>Staphylococcus aureus</i>Semantic proximity Read ↗

The fatty acid synthesis pathway is a checkpoint for lipoteichoic acid synthesis in <i>Staphylococcus aureus</i>Semantic proximity Read ↗

Host-derived fatty acids activate type VII secretion in Staphylococcus aureusSemantic proximity Read ↗

Antibiotic-induced accumulation of lipid II sensitizes bacteria to antimicrobial fatty acidsSemantic proximity Read ↗

Clinical Relevance of Type II Fatty Acid Synthesis Bypass in Staphylococcus aureusSemantic proximity Read ↗

Environmental fatty acids enable emergence of infectious Staphylococcus aureus resistant to FASII-targeted antimicrobials.Semantic proximity Read ↗

The Staphylococcus aureus Response to Unsaturated Long Chain Free Fatty Acids: Survival Mechanisms and Virulence ImplicationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.