Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cell Wall Remodeling by a Synthetic Analog Reveals Metabolic Adaptation in Vancomycin Resistant Enterococci.

ACS chemical biology - 21 Jul 2017

Pidgeon Sean E, Pires Marcos M

Abstract excerpt

Drug-resistant bacterial infections threaten to overburden our healthcare system and disrupt modern medicine. A large class of potent antibiotics, including vancomycin, operate by interfering with bacterial cell wall biosynthesis. Vancomycin-resistant enterococci (VRE) evade the blockage of cell wall biosynthesis by altering cell wall precursors, rendering them drug insensitive. Herein, we reveal the phenotypic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptation, Physiological
Share to Anti-Bacterial Agents
Share to Cell Wall

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Bacterial

Share to Phenotype

Share to Vancomycin

Share to Vancomycin Resistance

Share to Vancomycin-Resistant Enterococci

Source

Identifiers

PMID: 28574692
DOI: 10.1021/acschembio.7b00412

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cell Wall Remodeling by a Synthetic Analog Reveals Metabolic Adaptation in Vancomycin Resistant Enterococci.PMID 28574692Read ↗

Genetic and pharmacological inactivation of peptidoglycan remodeling increases antibiotic susceptibility of vancomycin-resistant <i>Enterococcus faecium</i>Semantic proximity Read ↗

Metabolic Mitigation of Staphylococcus aureus Vancomycin Intermediate-Level SusceptibilitySemantic proximity Read ↗

Unraveling the Protein Targets of Vancomycin in Living S. aureus and E. faecalis CellsSemantic proximity Read ↗

Mechanisms of vancomycin resistance in Staphylococcus aureus.Semantic proximity Read ↗

Disrupting central carbon metabolism increases antibiotic susceptibility in <i>Vibrio cholerae</i>Semantic proximity Read ↗

Transposon Screen of Surface Accessibility in <i>S. aureus</i>Semantic proximity Read ↗

Selective Bacteriocins: A Promising Treatment for Staphylococcus aureus Skin Infections Reveals Insights into Resistant Mutants, Vancomycin Resistance, and Cell Wall AlterationsSemantic proximity Read ↗

Antibiotic-induced accumulation of lipid II sensitizes bacteria to antimicrobial fatty acidsSemantic proximity Read ↗

Genomic and phenotypic adaptations of methicillin resistant Staphylococcus aureus during vancomycin therapySemantic proximity Read ↗

Understanding tolerance to cell wall–active antibioticsSemantic proximity Read ↗

Disrupting Central Carbon Metabolism Increases β-Lactam Antibiotic Susceptibility in Vibrio cholerae.Semantic proximity Read ↗

Preliminary analysis of the genetic basis for vancomycin resistance in Staphylococcus aureus strain Mu50.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.