Article
Staphylococcus aureus Utilizes Host-Derived Lipoprotein Particles as Sources of Fatty Acids.
Journal of bacteriology - 1 Jun 2018
Delekta Phillip C, Shook John C, Lydic Todd A, Mulks Martha H, Hammer Neal D
Abstract excerpt
Methicillin-resistant Staphylococcus aureus (MRSA) is a threat to global health. Consequently, much effort has focused on the development of new antimicrobials that target novel aspects of S. aureus physiology. Fatty acids are required to maintain cell viability, and bacteria synthesize fatty acids using the type II fatty acid synthesis (FASII) pathway. FASII is significantly different from human fatty acid...
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