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Induction of Daptomycin Tolerance in Enterococcus faecalis by Fatty Acid Combinations

17 Aug 2020

Abstract excerpt

With an increasing prevalence of antibiotic resistance in the clinic, we strive to understand more about microbial defensive mechanisms. A nongenetic tolerance to the antibiotic daptomycin was discovered in Enterococcus faecalis that results in the increased survival of bacterial populations after treatment with the drug. This tolerance mechanism likely synergizes with antibiotic resistance in the clinic. Given...

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PMID: 32801181
DOI: 10.1128/aem.01178-20

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