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Mrgprb4-Lineage Neurons Participate in Intervention of TENS on Chronic Pain and Anxiety-like Symptoms in Inflammatory Pain Mice Model

2026-01-21

Abstract excerpt

<h4>Background: </h4> Mas-related G-protein-coupled receptor b4 (Mrgprb4)-lineage neurons in the peripheral nervous system, were a type of C fibers in the hairy skin. Our prior work demonstrated that these neurons respond to both noxious and innocuous mechanical and thermal stimuli. Ablating them eliminates the pleasant sensation elicited by gentle pressure on the mouse nape. However, their potential role in mitig...

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Identifiers and source

Literature Corpus work
679dc496-9b77-56c7-969c-08630c169988
DOI
10.20944/preprints202601.1632.v1
Open publication

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Mrgprb4-Lineage Neurons Participate in Intervention of TENS on Chronic Pain and Anxiety-like Symptoms in Inflammatory Pain Mice ModelDOI 10.20944/preprints202601.1632.v1
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