Article

Prediction of Risk for Myeloid Malignancy in Clonal Hematopoiesis

2022-11-15

Abstract excerpt

Background Clonal hematopoiesis (CH), a precursor to myeloid malignancies, is extremely common. Formally defined CH subtypes, categorized by somatic mutations in genes associated with myeloid neoplasia (MN) at a variant allele fraction (VAF) ≥ 0.02, include clonal hematopoiesis of indeterminate potential (CHIP) where no cytopenia is present and clonal cytopenia of uncertain significance (CCUS). The rate of diagnos...

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Literature Corpus work: 67886fd7-9a3f-5f0f-8fda-e095f5575e8a
DOI: 10.1182/blood-2022-158960

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