Article

Approaches to estimating inbreeding coefficients in clinical isolates of Plasmodium falciparum from genomic sequence data

2015-06-25

Abstract excerpt

The advent of whole-genome sequencing has generated increased interest in modeling the structure of strain mixture within clinicial infections of Plasmodium falciparum (Pf). The life cycle of the parasite implies that the mixture of multiple strains within an infected individual is related to the out-crossing rate across populations, making methods for measuring this process in situ central to understanding the...

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Literature Corpus work: 677cf606-3ffa-5bbb-b39a-7a8d309385a9
DOI: 10.1101/021519

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