Article
Evidence of strain structure in Plasmodium falciparum var gene repertoires in children from Gabon, West Africa.
Proceedings of the National Academy of Sciences of the United States of America - 16 May 2017
Day Karen P, Artzy-Randrup Yael, Tiedje Kathryn E, Rougeron Virginie, Chen Donald S, Rask Thomas S, Rorick Mary M, Migot-Nabias Florence, Deloron Philippe, Luty Adrian J F, Pascual Mercedes
Abstract excerpt
Existing theory on competition for hosts between pathogen strains has proposed that immune selection can lead to the maintenance of strain structure consisting of discrete, weakly overlapping antigenic repertoires. This prediction of strain theory has conceptual overlap with fundamental ideas in ecology on niche partitioning and limiting similarity between coexisting species in an ecosystem, which oppose the...
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