Article
A model-based approach to characterize individual inbreeding at both global and local genomic scales.
Molecular ecology - 1 Oct 2017
Druet T, Gautier M
Abstract excerpt
Inbreeding results from the mating of related individuals and may be associated with reduced fitness because it brings together deleterious variants in one individual. In general, inbreeding is estimated with respect to an arbitrary base population consisting of ancestors that are assumed unrelated. We herein propose a model-based approach to estimate and characterize individual inbreeding at both global and...
Topics
- Animals
- Computer Simulation
- Dogs
- Gene Frequency
- Genetic Fitness
- Genotype
- Homozygote
- Humans
- Inbreeding
- Models, Genetic
- Sheep