Article

GLP-1 Notch - LAG-1 CSL control of the germline stem cell fate is mediated by transcriptional targets <i>lst-1</i> and <i>sygl-1</i>

2019-10-31

Abstract excerpt

Stem cell systems are essential for the development and maintenance of polarized tissues. Intercellular signaling pathways control stem cell systems, where niche cells signal stem cells to maintain the stem cell fate/self renewal and inhibit differentiation. In the C. elegans germline, GLP-1 Notch signaling specifies the stem cell fate. We undertook a comprehensive genome-wide approach to identify transcriptional...

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Literature Corpus work: 6772f065-80c7-5a1e-8521-7288541c091a
DOI: 10.1101/825232

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