Article

C. elegans germline stem cells and their niche

2014-01-01

Abstract excerpt

C. elegans germline stem cells are a particularly simple system for analysis of stem cell regulation. Their well-defined mesenchymal niche consists of a single cell, the Distal Tip Cell, which uses Notch signaling to maintain a pool of germline stem cells. Downstream of Notch signaling a post-transcriptional regulatory network dictates self-renewal or differentiation. The major self-renewal hub of that network is...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a77c08c6-aae3-5f2f-a84e-20ef6e1c2c16
DOI: 10.3824/stembook.1.95.1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

C. elegans germline stem cells and their nicheDOI 10.3824/stembook.1.95.1Read

Germline proliferation and its controlSemantic proximity Read

<i>Caenorhabditis elegans</i> as a model for stem cell biologySemantic proximity Read

C. elegans germ cells divide and differentiate in a folded tissueSemantic proximity Read

A PUF Hub Drives Self-Renewal in Caenorhabditis elegans Germline Stem Cells.Semantic proximity Read

Progression from a stem cell-like state to early differentiation in the C. elegans germ line.Semantic proximity Read

A conserved RNA-binding protein controls germline stem cells in Caenorhabditis elegans.Semantic proximity Read

Identification of regulators of germ stem cell enwrapment by its niche in C. elegansSemantic proximity Read

Controls of Germline Stem Cells, Entry into Meiosis, and the Sperm/Oocyte Decision in<i>Caenorhabditis elegans</i>Semantic proximity Read

Scratching the niche that controls Caenorhabditis elegans germline stem cellsSemantic proximity Read

Recent Advances in the Genetic, Anatomical, and Environmental Regulation of the C. elegans Germ Line Progenitor ZoneSemantic proximity Read

The C. elegans adult male germline: Stem cells and sexual dimorphismSemantic proximity Read

Stem cell niche exit in C. elegans via orientation and segregation of daughter cells by a cryptic cell outside the nicheSemantic proximity Read