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Article

Controls of Germline Stem Cells, Entry into Meiosis, and the Sperm/Oocyte Decision in<i>Caenorhabditis elegans</i>

25 Jun 2007

Abstract excerpt

The Caenorhabditis elegans germ line provides an exceptional model for analysis of the molecular controls governing stem cell maintenance, the cell cycle transition from mitosis to meiosis, and the choice of sexual identity-sperm or oocyte. Germline stem cells are maintained in an undifferentiated state within a well-defined niche formed by a single somatic cell, the distal tip cell (DTC). In both sexes, the DTC...

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Identifiers

PMID: 17506698
DOI: 10.1146/annurev.cellbio.23.090506.123326

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