Article

Spontaneous Remission and Clonal Relapse in Congenital Infant Leukemia: Single-Cell Atlas Profiling and Curative Transplantation

2025-12-16

Abstract excerpt

<title>Abstract</title> <p>Congenital leukemia is an exceptionally rare malignancy with an incidence below five per million births and poor prognosis, especially in cases with KMT2A rearrangements. Spontaneous remission (SR) is an uncommon phenomenon; since 1996, only five SR cases with KMT2A rearrangements have been reported worldwide. We describe a neonate with congenital AML-M5 carrying a KMT2A-MLLT3 fusion, w...

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Literature Corpus work: 671b283f-cc21-5321-948a-e8d74010e8ed
DOI: 10.21203/rs.3.rs-7714797/v1

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