Article

Single cell analysis reveals altered tumor microenvironments of relapse- and remission-associated pediatric acute myeloid leukemia

2021-09-03

Abstract excerpt

<title>Abstract</title> <p>Relapse- and continuous complete remission (CCR)-associated pediatric acute myeloid leukemia (AML) patient bone marrows collected at the time of diagnosis (Dx), end of induction (EOI) and relapse were analyzed by single cell RNA sequencing. A novel AML blasts-associated 7-genes signature (CLEC11A, PRAME, AZU1, NREP, ARMH1, C1QBP, TRH) displayed a strong correlation with blast percentage...

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Literature Corpus work: 759a61f4-eec2-508e-99aa-beab65e21093
DOI: 10.21203/rs.3.rs-819846/v2

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