Article

Disentangling protein metabolic costs in human cells and tissues

2023-06-05

Abstract excerpt

Many intrinsic functional characteristics of cells and tissues shape their genome-wide expression patterns. But what other factors might also modulate these patterns are not fully known. Here, we revisit the general model of costs in which the protein products of highly expressed genes should be short and made up of biosynthetically cheap amino acids. We first use single-cell expression data from a collection of h...

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Literature Corpus work: 66f5fb7a-5115-5c32-9a12-2b6043b8b761
DOI: 10.1101/2023.06.05.543683

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