Article

C57BL/6 and 129 inbred mouse strains differ in Gbp2 and Gbp2b expression in response to inflammatory stimuli in vivo

2019-08-20

Abstract excerpt

<h4>Background: </h4> : Infections cause the production of inflammatory cytokines such as Interferon gamma (IFNγ). IFNγ in turn prompts the upregulation of a range of host defence proteins including members of the family of guanylate binding proteins (Gbps). In humans and mice alike, GBPs restrict the intracellular replication of invasive microbes and promote inflammation. To study the physiological functions of G...

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Literature Corpus work: 668693da-b171-5795-9ca1-6fe382beb7d1
DOI: 10.12688/wellcomeopenres.15329.1

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C57BL/6 and 129 inbred mouse strains differ in Gbp2 and Gbp2b expression in response to inflammatory stimuli in vivoDOI 10.12688/wellcomeopenres.15329.1Read

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