Article
Murine GBP-5, a New Member of the Murine Guanylate-Binding Protein Family, Is Coordinately Regulated with Other GBPs In Vivo and In Vitro
1 Aug 2002
Abstract excerpt
A new murine member of the interferon (IFN)-inducible guanylate-binding protein (GBP) family was cloned in a search for glucocorticoid-attenuated response genes induced in the lung during endotoxemia. The full-length MuGBP-5 cDNA encodes a 590 amino acid residue protein with GTP binding motifs identical to those in human GBP-1 (HuGBP-1) and a similar isoprenylation sequence at the C-terminus. An alternatively...
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