Variations in the germinal center response revealed by genetically diverse mouse strains.

doi:10.1111/imcb.12823

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Article

Variations in the germinal center response revealed by genetically diverse mouse strains.

Immunology and cell biology - 1 Nov 2024

Aubin Anne-Marie, Vdovenko Daria, Collin Roxanne, Balmer Lois, Coderre Lise, Morahan Grant, Lombard-Vadnais Félix, Lesage Sylvie

Abstract excerpt

The humoral response is complex and involves multiple cellular populations and signaling pathways. Bacterial and viral infections, as well as immunization regimens, can trigger this type of response, promoting the formation of microanatomical cellular structures called germinal centers (GCs). GCs formed in secondary lymphoid organs support the differentiation of high-affinity plasma cells and memory B cells....

Topics

Animals
Germinal Center
Mice
Genetic Variation
B-Lymphocytes
Spleen
Peyer's Patches
Plasma Cells
Immunity, Humoral
Lymph Nodes
Sheep
Immunization

Source

Open in PubMed

Identifiers

PMID: 39318030
DOI: 10.1111/imcb.12823

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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