Article

Incomplete Reprogramming of DNA Replication Timing in Induced Pluripotent Stem Cells

2023-06-12

Abstract excerpt

Induced pluripotent stem cells (iPSC) are a widely used cell system and a foundation for cell therapy. Differences in gene expression, DNA methylation, and chromatin conformation, which have the potential to affect differentiation capacity, have been identified between iPSCs and embryonic stem cells (ESCs). Less is known about whether DNA replication timing – a process linked to both genome regulation and genome s...

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Literature Corpus work: 65f07ad9-d70b-5fe0-bab6-73b5e5d3660c
DOI: 10.1101/2023.06.12.544654

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