Article

Tristetraprolin prevents gastric metaplasia in mice by suppressing pathogenic inflammation

2021-01-21

Abstract excerpt

Aberrant immune activation is associated with numerous inflammatory and autoimmune diseases and contributes to cancer development and progression. Within the stomach, inflammation drives a well-established sequence from gastritis to metaplasia, eventually resulting in adenocarcinoma. Unfortunately, the processes that regulate gastric inflammation and prevent carcinogenesis remain unknown. Tristetraprolin (TTP) is...

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Literature Corpus work: 64ccb6b9-c2cc-5bd8-9a50-824836de4e07
DOI: 10.1101/2021.01.21.427435

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