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Tristetraprolin-mediated mRNA destabilization regulates basophil inflammatory responses

15 Nov 2024

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BACKGROUND: Basophils, despite being the least common granulocytes, play crucial roles in type 2 immune responses, such as chronic allergic inflammation and protective immunity against parasites. However, the molecular mechanisms regulating basophil activation and inflammatory molecule production remain poorly understood. Therefore, we investigated the role of RNA-binding proteins, specifically tristetraprolin...

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PMID: 39550253
DOI: 10.1016/j.alit.2024.10.005

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