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BRIDGE: A Multi-organ Histo-ST Foundation Model Enables Virtual Spatial Transcriptomics for Enhanced Few-shot Cancer Diagnosis

2026-05-08

Abstract excerpt

<h4>SUMMARY</h4> Recent studies have explored generating virtual spatial transcriptomics (ST) profiles from histological images, offering a promising alternative to laboratory-measured molecular profiling. However, existing approaches predominantly rely on single-organ models and require sub-stantial organ-specific training data, restricting their accuracy under challenging few-shot conditions in clincical practi...

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Literature Corpus work
64cbf5f8-2fda-513d-8287-8ee988cf3566
DOI
10.64898/2026.05.05.722971
Open publication

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