Article

Integrating Histology with Spatial Molecular Programs Using a Multimodal Foundation Model

2026-06-03

Abstract excerpt

Histopathological assessment remains central to cancer diagnosis and stratification, yet its mechanistic interpretation remains limited without molecular context. To address this, we developed SQUALL, a multimodal foundation model integrating histology with spatial molecular programs. For pretraining, we assembled histMol , a large-scale corpus of 1.76 billion paired histology-spatial transcriptomics spots/bins a...

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Literature Corpus work: a78673f4-6103-56ff-9eed-ae480c650dcf
DOI: 10.64898/2026.06.01.729028

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