Article

SpatialFinder: A Human-in-the-Loop Vision-Language Framework for Prioritizing High-Value Regions in Spatial Transcriptomics

2025-08-21

Abstract excerpt

Sequencing an entire spatial transcriptomics slide can cost thousands of dollars per assay, making routine use impractical. Focusing on smaller regions of interest (ROIs) based on adjacent routine H&E slides offers a practical alternative, but there is (i) no reliable way to identify the most informative areas from standard H&E images alone; and (ii) limited solutions for clinicians to prioritize the microenvironm...

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Literature Corpus work: 20233f0a-68f7-5bf5-a33e-7f5fc07998c0
DOI: 10.1101/2025.08.16.670684

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