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A technical comparison of spatial transcriptomics platforms across six cancer types

12 Jan 2026

Abstract excerpt

BACKGROUND: Spatial transcriptomics (ST) technologies are reshaping our understanding of tissue organization and cellular context in health and disease. However, technical benchmarking across platforms remains limited, particularly in formalin-fixed, paraffin-embedded (FFPE) clinical samples, which represent the most common tissue format in oncology. RESULTS: Here, we systematically benchmark five commercial ST...

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PMID: 41526977
DOI: 10.1186/s13059-026-03937-y

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