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STPath: A Generative Foundation Model for Integrating Spatial Transcriptomics and Whole Slide Images

2025-04-24

Abstract excerpt

Spatial transcriptomics (ST) has shown remarkable promise in pathology applications, shedding light on the spatial organization of gene expression and its relationship to the tumor microenvironment. However, its clinical adoption remains constrained due to the limited scalability of current sequencing technologies. While recent methods attempt to infer ST from whole slide images (WSIs) using pretrained image encod...

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Identifiers and source

Literature Corpus work
79fb265a-5e1b-598c-9a24-7e91112c4224
DOI
10.1101/2025.04.19.649665
Open publication

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STPath: A Generative Foundation Model for Integrating Spatial Transcriptomics and Whole Slide ImagesDOI 10.1101/2025.04.19.649665
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