Article

PathOmCLIP: Connecting tumor histology with spatial gene expression via locally enhanced contrastive learning of Pathology and Single-cell foundation model

2024-12-11

Abstract excerpt

Tumor morphological features from histology images are a cornerstone of clinical pathology, diagnostic biomarkers, and basic cancer biology research. Spatial transcriptomics, which provides spatially resolved gene expression profiles overlaid on histology images, offers a unique opportunity to integrate morphological and expression features, thereby deepening our understanding of tumor biology. However, spatial tr...

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Literature Corpus work: dfbdcde7-a36d-5933-af15-25767987d443
DOI: 10.1101/2024.12.10.627865

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