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Functional characterization of six <i>SLCO1B1</i> (OATP1B1) variants observed in Finnish individuals with a psychotic disorder

2022-08-10

Abstract excerpt

<h4>Aim</h4> Variants in the SLCO1B1 (solute carrier organic anion transporter family member 1B1) gene encoding the OATP1B1 (organic anion transporting polypeptide 1B1) protein are associated with altered transporter function that can predispose patients to adverse drug effects with statin treatment. We explored the effect of six rare SLCO1B1 single nucleotide variants (SNVs) occurring in Finnish individuals with...

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Literature Corpus work
648ccad8-e035-5af7-825c-9e01e29460b8
DOI
10.1101/2022.08.10.22278615
Open publication

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Functional characterization of six <i>SLCO1B1</i> (OATP1B1) variants observed in Finnish individuals with a psychotic disorderDOI 10.1101/2022.08.10.22278615
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