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Article

The landscape of allele-specific expression in human kidneys

2025-12-09

Abstract excerpt

Allele-specific expression (ASE), the preferential expression of one gene copy, is a key mechanism of genomic regulation. However, its role in human kidney disease remains poorly understood. In this study, we generated a high-quality, genome-wide ASE map using paired whole-genome sequencing and RNA-seq from microdissected glomerular (GLOM) and tubulointerstitial (TUBE) compartments of patients with proteinuric kid...

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Literature Corpus work
6484c5b3-e1b0-5af7-85e6-3fe18190ecd2
DOI
10.64898/2025.12.03.692205
Open publication

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The landscape of allele-specific expression in human kidneysDOI 10.64898/2025.12.03.692205
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