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Spatially resolved human kidney multi-omics single cell atlas highlights the key role of the fibrotic microenvironment in kidney disease progression

2022-10-26

Abstract excerpt

Kidneys possess one of the most intricate three-dimensional cellular structures in the body, yet the spatial and molecular principles of kidney health and disease remain inadequately understood. Here, we have generated high-quality datasets for 81 samples, including single cell (sc), single nuclear (sn), spot level (Visium) and single cell resolution (CosMx) spatial (sp)-RNA expression, and sn open chromatin, capt...

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Identifiers and source

Literature Corpus work
296abe37-df9f-5606-8986-17e1f76ff0f8
DOI
10.1101/2022.10.24.513598
Open publication

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Spatially resolved human kidney multi-omics single cell atlas highlights the key role of the fibrotic microenvironment in kidney disease progressionDOI 10.1101/2022.10.24.513598
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