Article

Diverse Patterns of Allele-Specific Expression in Healthy Human Tissues

2025-10-14

Abstract excerpt

Differences in gene sequence and gene expression underlie variation in traits. However, even monozygotic twins do not express their genes in the same way, develop divergence in traits, and succumb to distinct chronic diseases. During development, epigenetic silencing programs cause diversity in allele expression, resulting in differences in traits and chronic disease risk. To quantify human autosomal allele expres...

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Literature Corpus work: 58809c7b-512d-55c9-ada8-47e6b10e80d5
DOI: 10.1101/2025.10.14.682127

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