Article

YY1 Promotes Pancreatic Cancer Cell proliferation by Enhancing Mitochondrial Respiration

2022-03-22

Abstract excerpt

KRAS -driven metabolic reprogramming is one of the key features of pancreatic ductal adenocarcinoma (PDAC) cells; however, the metabolic roles of other oncogenic genes, such as YY1 , in PDAC development are still unclear. In this study, we observed that YY1 expression was significantly elevated in human PDAC tissues and was positively correlated with a poor disease progression. Further, in vitro studies confirmed...

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Literature Corpus work: 64450191-9748-532d-8577-c0380cb11013
DOI: 10.21203/rs.3.rs-1466742/v1

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