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Metabolism of Amino Acids in Cancer

12 Jan 2021

Abstract excerpt

Metabolic reprogramming has been widely recognized as a hallmark of malignancy. The uptake and metabolism of amino acids are aberrantly upregulated in many cancers that display addiction to particular amino acids. Amino acids facilitate the survival and proliferation of cancer cells under genotoxic, oxidative, and nutritional stress. Thus, targeting amino acid metabolism is becoming a potential therapeutic...

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PMID: 33511116
DOI: 10.3389/fcell.2020.603837

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