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Article

The biological role of metabolic reprogramming in pancreatic cancer

5 Nov 2020

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease and highly resistant to all forms of therapy. PDAC cells reprogram their metabolism extensively to promote their survival and growth. Reflecting the vital role of altered metabolism, experimental and clinical trials targeting the rewired metabolism are currently underway. In this review, we summarize the vital role of metabolic reprogramming in the...

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Share to Cancer, Hypoxia, and Metabolism
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PMID: 34766124
DOI: 10.1002/mco2.37

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