Article

A model for <i>cis</i> -regulation of transcriptional condensates and gene expression by proximal lncRNAs

2023-01-04

Abstract excerpt

<h4>ABSTRACT</h4> Long non-coding RNAs (lncRNAs) perform several important functions in cells including cis-regulation of transcription. Barring a few specific cases, the mechanisms underlying transcriptional regulation by lncRNAs remain poorly understood. Transcriptional proteins can form condensates via phase separation at protein-binding loci (BL) on the genome (e.g., enhancers and promoters). lncRNA-coding ge...

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Literature Corpus work: 643185ae-4b30-5baf-927e-a9b939e80cf9
DOI: 10.1101/2023.01.04.522753

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