Article

Ablation of GM3 Gangliosides in cardiomyocytes modestly impacts heart size but does not protect the murine heart against ischemia reperfusion injury

2026-07-18

Abstract excerpt

Advances in mass spectrometry have seen the identification of hundreds of new lipid species, some of which have been found to be associated with adverse cardiac remodeling. Key among these are GM3 gangliosides, which have been associated with metabolic disease, and more recently, adverse cardiac remodeling. Whether GM3s have a direct pathophysiological effect in the heart remains unclear. The present study investi...

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Literature Corpus work: 63f796f6-b9c4-5a0c-ac7f-9454d355538c
DOI: 10.64898/2026.07.13.738350

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Ablation of GM3 Gangliosides in cardiomyocytes modestly impacts heart size but does not protect the murine heart against ischemia reperfusion injuryDOI 10.64898/2026.07.13.738350Read

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