Article
Evaluating sex-specific responses to western diet across the lifespan: impact on cardiac function and transcriptomic signatures in C57BL/6J mice at 530 and 640/750 days of age.
Cardiovascular diabetology - 28 Dec 2024
Stepanyan Ani, Brojakowska Agnieszka, Zakharyan Roksana, Hakobyan Siras, Davitavyan Suren, Sirunyan Tamara, Khachatryan Gisane, Khlgatian Mary K, Bisserier Malik, Zhang Shihong, Sahoo Susmita, Hadri Lahouaria, Rai Amit, Garikipati Venkata Naga Srikanth, Arakelyan Arsen, Goukassian David A
Abstract excerpt
BACKGROUND: Long-term consumption of Western Diet (WD) is a well-established risk factor for the development of cardiovascular disease (CVD); however, there is a paucity of studies on the long-term effects of WD on the pathophysiology of CVD and sex-specific responses. METHODS: Our study aimed to investigate the sex-specific pathophysiological changes in left ventricular (LV) function using transthoracic...
Topics
Join the communities discussing this publication.