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Article

Integrated Myocardial and Plasma Lipidome Across the Human Obesity–Heart Failure Spectrum

2026-07-17

Abstract excerpt

<title>Abstract</title> <p>Heart failure with preserved ejection fraction (HFpEF) has become the dominant heart failure phenotype, with many patients impacted by marked obesity. Lipid dyshomeostasis is thought to contribute, but human myocardial lipidomic data remain lacking. We performed untargeted lipidomics (>1,000 species) of ventricular samples for non-failing (NF) controls (n=40), HFpEF (n=29), and HFrEF (n...

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Literature Corpus work
6c9858d6-09fb-5845-a62b-e4936865731d
DOI
10.21203/rs.3.rs-10157404/v1
Open publication

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Integrated Myocardial and Plasma Lipidome Across the Human Obesity–Heart Failure SpectrumDOI 10.21203/rs.3.rs-10157404/v1
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