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The pivotal role of the X-chromosome in the genetic architecture of the human brain

2023-09-01

Abstract excerpt

Genes on the X-chromosome are extensively expressed in the human brain. However, little is known for the X-chromosome’s impact on the brain anatomy, microstructure, and functional network. We examined 1,045 complex brain imaging traits from 38,529 participants in the UK Biobank. We unveiled potential autosome-X-chromosome interactions, while proposing an atlas outlining dosage compensation (DC) for brain imaging t...

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Literature Corpus work
63c2e1b9-27d1-551d-943d-3329531ea41c
DOI
10.1101/2023.08.30.23294848
Open publication

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The pivotal role of the X-chromosome in the genetic architecture of the human brainDOI 10.1101/2023.08.30.23294848
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