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Article

The effect of X-linked dosage compensation on complex trait variation

2018-10-03

Abstract excerpt

<h4>Summary</h4> Quantitative genetics theory predicts that X-chromosome dosage compensation between sexes will have a detectable effect on the amount of genetic and therefore phenotypic trait variances at associated loci in males and females. Here, we systematically examine the role of dosage compensation in complex trait variation in humans in 20 complex traits in a sample of more than 450,000 individuals from...

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Literature Corpus work
0a4838e5-6d2d-5461-aa53-20b1fd1cbb50
DOI
10.1101/433870
Open publication

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The effect of X-linked dosage compensation on complex trait variationDOI 10.1101/433870
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