Article

Genetically predicted plasma erythropoietin levels and clonal haematopoiesis risk: a Mendelian randomisation study

2024-11-20

Abstract excerpt

<h4>ABSTRACT</h4> The aetiology of clonal haematopoiesis (CH) and its progression to haematological malignancies is poorly understood. Erythropoietin (EPO) has been linked to favourable haematopoietic stem and progenitor cell clonal compositions in mice and humans, but a direct large-scale assessment of its role in CH is lacking. We evaluated the association between plasma EPO levels and overall, DNMT3A - and TET2...

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Literature Corpus work: 63b527fe-54c3-5d5e-94b0-4571ab912ae6
DOI: 10.1101/2024.11.19.24317548

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