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A Mendelian randomization study of telomere length and blood-cell traits

2020-06-03

Abstract excerpt

Whether telomere attrition reducing proliferative reserve in blood-cell progenitors is causal has important public-health implications. Mendelian randomization (MR) is an analytic technique using germline genetic variants as instrumental variables. If certain assumptions are met, estimates from MR should be free from most environmental sources of confounding and reverse causation. Here, two-sample MR is performed...

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Literature Corpus work
2e676cbf-3745-573d-bc3c-639f06a5fa1c
DOI
10.1101/2020.05.30.20117978
Open publication

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A Mendelian randomization study of telomere length and blood-cell traitsDOI 10.1101/2020.05.30.20117978
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