Article
Clonal hematopoiesis in frequent whole blood donors.
Hematology. American Society of Hematology. Education Program - 8 Dec 2023
Karpova Darja
Abstract excerpt
Healthy volunteer donors are committed to contributing key medical resources. Repeated, regular donation of whole blood represents a specific trigger of hematopoietic stress. Hematopoietic stem cells (HSCs) are known to respond to environmental triggers by altering their differentiation and/or proliferative behavior. This can manifest in long-term changes in the clonal dynamics of HSCs, such as the age-associated...
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