Article

Cutting down the time to identify challenging tumor therapeutic targets and drug combinations using synthetic lethal approaches

2018-03-12

Abstract excerpt

Cancer drug discoverers and developers are blessed and cursed with a plethora of drug targets in the tumor cells themselves and the surrounding stromal elements. This bounty of targets has, at least in part, inspired the rapid increase in the number of clinically available small-molecule, biological, and cellular therapies for solid and hematological malignancies. Among the most challenging questions in cancer the...

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Literature Corpus work: 6375942e-2346-59f5-98bf-2ff0c6afc3bb
DOI: 10.12688/f1000research.13679.1

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