Article
A lethal combination for cancer cells: synthetic lethality screenings for drug discovery.
European journal of cancer (Oxford, England : 1990) - 1 Nov 2010
Ferrari Elisa, Lucca Chiara, Foiani Marco
Abstract excerpt
In recent years, cancer drug discovery has faced the challenging task of integrating the huge amount of information coming from the genomic studies with the need of developing highly selective target-based strategies within the context of tumour cells that experience massive genome instability. The combination between genetic and genomic technologies has been extremely useful and has contributed to efficiently...
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